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NOVEL PHENYLPYRIDINE DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME
专利权人:
发明人:
申请号:
EP10820125.2
公开号:
EP2484675B1
申请日:
2010.09.29
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Disclosed are: a novel compound which has both an antagonistic activity on an angiotensin II receptor and a PPARγ-activating activity and is therefore useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, arteriosclerosis, type-2 diabetes, diabetic complications, metabolic syndrome or the like and a pharmaceutical composition containing the compound. Specifically disclosed are: a compound represented by general formula (I) (wherein the ring A represents a pyridine ring the ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring X represents C-R5 or a nitrogen atom R1 represents a C1-6 alkyl group R2 represents a C1-6 alkyl group or a C3-8 cycloalkyl group and R3, R4, R5 independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group, a halo-C1-6 alkyl group, or a C1-6 alkoxy group which may have a substituent), a salt of the compound, or a solvate of the compound or the salt and a pharmaceutical composition containing the compound, the salt or the solvate.
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