Yeda Research and Development Co., Ltd.;The Medical Research, Infrastructure, and Health Services Fund of the Tel-Aviv Medical Center
发明人:
申请号:
EP18712421.9
公开号:
EP3589729A1
申请日:
2018.03.02
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Methods of culturing T cells are provided. Accordingly there is provided a method of culturing T cells comprising culturing T cells in the presence of a T cell stimulator, an exogenous CCL21 and an exogenous ICAM1, thereby culturing the T cells. Also provided are cell cultures, isolated T cells and uses of same.L'invention concerne des méthodes de culture de lymphocytes T. Ainsi, l'invention concerne une méthode de culture de lymphocytes T comprenant la culture de lymphocytes T en présence d'un stimulateur de lymphocytes T, d'un CCL21 exogène et d'un ICAM1 exogène, ce qui permet la culture des lymphocytes T. L'invention concerne également des cultures cellulaires, des lymphocytes T isolés et leurs utilisations.