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Combinations comprising a diaryl urea and an interferon
专利权人:
发明人:
申请号:
EP10011899.1
公开号:
EP2289515A3
申请日:
2006.10.31
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention provides methods for treating cancer in humans and other mammals comprising administering a chemotherapeutic agent, such as an interferon, and an aryl urea compound of Formula (I) :         B-NH-C(O)-NH-L-M-L1-(Q)1-3     (I).In Formula (I), B and L and are each, independently, optionally substituted phenyl, naphthyl, a 5 or 6 membered monocyclic heteroaryl group, or an 8 to 10 membered bicyclic heteroaryl groupM is a bridging group.each Q is independently C(O)R4, C(O)OR4 and C(O)NR4R5 and L is optionally substituted phenyl, naphthyl, monocyclic heteroaryl or bicyclic heteroaryl, or a saturated or partially saturated, monocyclic or bicyclic carbocyclic moiety or heterocyclic moiety.
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