環状エーテル・アミド化合物。

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专利权人:

独立行政法人産業技術総合研究所

发明人:

芝上 基成,三由 伸

申请号：

JP2006355091

公开号：

JP5004075B2

申请日:

2006.12.28

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a new cyclic ether amide lipid constructing molecular aggregates by self-organization, and a lipid membrane forming a moderate intramolecular hydrogen bond.

SOLUTION: This new cyclic ether amide lipid of 2 glycerol derivatives and 2 long chain alkyl compounds, having a diether bond backbone and an amide bond backbone simultaneously is obtained by synthesizing a diether lipid of a glycerol derivative building-in asymmetric groups and the long chain alkyl compound and then passing through a new intermediate material obtained by introducing an azide group having high reactivity. The obtained cyclic ether amide lipid is provided by forming the molecular aggregates by the self-organization, having a property close to that of a cyclic amide lipid and forming a lipid membrane having a somewhat weakened intramolecular hydrogen bond.

COPYRIGHT: (C)2008,JPO&INPIT

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