Aqueous composition comprises: vesicles formed from at least one amphiphilic, membrane-forming lipid of the group of esters or diacylglycerides polyacylglycerides with long-chain unsaturated fatty acids and at least one membrane-stabilizing long-chain unsaturated fatty acid monoester; an aqueous medium comprising both the vesicle and carrier vehicle of the same composition; at least one active substance which can be hydrophilic, amphiphilic or lipophilic.