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Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
专利权人:
Su-Chun Zhang
发明人:
Su-Chun Zhang,Xue-jun Li
申请号:
US13068285
公开号:
US09080151B2
申请日:
2011.05.06
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of differentiating embryonic stem cells into neural and motor cells is disclosed. In one embodiment, the invention comprises culturing a population of cells comprising a majority of cells that are characterized by an early rosette morphology and are Sox1−/Pax6+ in the presence of FGF2, FGF4, FGF8, FGF 9, or RA wherein the cells are characterized by an neural tube-like rosette morphology and are Pax6+/Sox1+.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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