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COMPOSITIONS AND METHODS FOR TREATING NAIL DISEASES
专利权人:
ИНК. (US);ДОУ ФАРМАСЬЮТИКАЛ САЙЕНСИЗ
发明人:
ВИНКЛ Гэрет (US),ФИЛДСОН Грэгори Т. (US)
申请号:
RU2010131966/15
公开号:
RU2010131966A
申请日:
2008.12.30
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method of treating a violation of the nails or the nail bed, comprising topically applying to the nail surface of an individual suffering from the violation, a pharmaceutical composition comprising a carrier that is volatile and / or quickly penetrates the nail after application to the surface of the nail, a non-volatile solvent that is dissolved, suspended, dispersed or emulsified in a carrier, an active pharmaceutical ingredient (API), soluble in a non-volatile solvent or in a mixture of a non-volatile solvent and carrier, and wetting e means, and while applying the composition is produced in an amount and for a time sufficient to reduce the severity of the symptoms of the violation. ! 2. The method according to claim 1, characterized in that the wetting agent and the carrier are the same compound. ! 3. The method according to claim 1, characterized in that the wetting agent is a volatile silicone. ! 4. The method according to claim 1, characterized in that the carrier is an alcohol. ! 5. The method according to claim 1, characterized in that the non-volatile solvent is non-polar. ! 6. The method according to claim 5, characterized in that the non-volatile solvent is one or more esters of the formula RCO-OR ', where R and R' can be the same or different, and each of R and R 'is linear or a branched alkyl, alkenyl, alkoxycarbonylalkyl or alkoxycarbonyloxyalkyl radical containing from 1 to 25 carbon atoms. ! 7. The method according to claim 1, characterized in that the API is an antifungal agent. ! 8. The method according to claim 6, characterized in that the antifungal agent is a triazole compound. ! 9. The way1. Способ лечения нарушения ногтей или ногтевого ложа, включающий местное нанесение на поверхность ногтя индивидуума, страдающего указанным нарушением, фармацевтической композиции, содержащей носитель, который является летучим и/или быстро проникает в ноготь после нанесения на поверхность ногтя, нелетучий растворитель, который растворен, суспензирован, д
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