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UTILISATION DE L'ACIDE 2,5-DIHYDROXYBENZENESULFONIQUE DANS LA FABRICATION DE MEDICAMENTS UTILES POUR LE TRAITEMENT DE MALADIES ANGIODEPENDANTES
专利权人:
S.L.;ACTION MEDICINES
发明人:
CUEVAS SANCHEZ, PEDRO,ROMERO GARRIDO, ANTONIO,LOZANO PUERTO, ROSA MARIA,GIMENEZ GALLEDO, GUILLERMO,VALVERDE LOPEZ, SERAFIN
申请号:
CA2555248
公开号:
CA2555248C
申请日:
2005.02.16
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to the use of 2,5-dihydroxybenzenesulphonic acid in theproduction of medicaments for the treatment of angiodependent diseases. Morespecifically, the invention relates to the use of the aforementioned compoundand, in particular, the calcium and potassium salts thereof, for the treatmentof two angiodependent diseases which present a reduction in apoptosis, namelycancer and psoriasis. The invention also discloses the antiproliferative,antimigratory, antiangiogenic and proapoptotic capacity of said family ofcompounds in non-quiescent cells. In addition, the invention details thepotentiating effect of said compounds on known cytostatic medicines in thetreatment of tumours and, specifically, on gliomas. The invention furtherrelates to the therapeutic efficacy of said compounds, based on the combinedantiproliferative, antiangiogenic and proapoptotic capacities thereof, in thetreatment of chronic psoriatic plaques.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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