Pedro Cuevas Sànchez,Antonio Romero Garrido,Guillermo Gimenez Gallego,Serafin Valverde Lopez,Rosa Maria Lozano Puerto
申请号：
US13772790
公开号：
US20130203851A1
申请日:
2013.02.21
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for the treatment of angiodependent diseases. More specifically, described is the use of the aforesaid compound and, in particular, the calcium and potassium salts thereof, for the treatment of two angiodependent diseases, which present a reduction in the apoptosis, namely cancer and psoriasis. Also described is the antiproliferative, antimigratory, antiangiogenic and proapoptotic capacity of said family of compounds in non-quiescent cells. In addition, described is the potentiating effect of said compounds on known cytostatic medicines in the treatment of tumours and, specifically, on gliomas. Additionally, the therapeutic efficacy of said compounds, based on the combined anti proliferative, antiangiogenic and proapaptotic capacities thereof, in the treatment of chronic psoriatic plaques is provided.
