Method for inhibition of deubiquitinating activity

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专利权人:

Vivolux AB

发明人:

Linder, Stig,Larsson, Rolf

申请号：

AU2012326682

公开号：

AU2012326682A1

申请日:

2012.10.15

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

A compound of the general structure (I) is capable of abrogating the deubiquitinating (DUB) activity of the 19S RP DUBs. The compound can be used for treating cancer, in particular of cancer refractory to treatment by state-of-the-art chemotherapy. Also disclosed are corresponding methods of treatment and a pharmaceutical composition comprising the compound.

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