Herbal extract and compound lupinoside and its analogues as anti-diabetic type II drugs from plant Pueraria tuberosa

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专利权人:

COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

发明人:

DEY DEBLEENA,MANDAL SWAPAN KUMAR,MUKHERJEE MOHUA,PAL BIKASH CHANDRA,BISWAS TANUSHREE,DATTA MALABIKA,ROY SIB SANKAR,BANDYOPADHYAY ARUN,BHATTACHARYA SAMIR,GIRI BIR BHANU,BANDOPADHYAY SANTU,KONAR ADITYA

申请号：

US20040809645

公开号：

US7276258(B2)

申请日:

2004.03.25

申请国别(地区):

美国

年份:

2007

代理人:

摘要：

The present invention relates to a method of preventing and/or treating diabetes type 2, also, it relates to a method of augmenting Glut4 phosphorylation and Glut4 translocation to a target cell membrane to enhance insulin signal in a signal transduction pathway; further, it relates to a simplified and inexpensive process of obtaining extract and thereafter selectively, its active n-butanol fraction and active molecule Lupinoside PA (LPA₄), useful in preventing and/or treating diabetes type 2; and lastly, a pharmaceutical composition thereof.

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