Jianhua SUN,Christophe BUREAU,Wenbin CAI,Tianzhu LI,Xiaoran KANG
申请号：
US16472779
公开号：
US20190365959A1
申请日:
2017.10.30
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Drug eluting stents, methods of making, using, and verifying long-term stability of the drug eluting stents, and methods for predicting long term stent efficacy and patient safety after implantation of a drug eluting stent are disclosured. In one embodiment, a drug eluting stent may include a stent framework； a drug-containing layer； a drug embedded in the drug-containing layer； and a biocompatible base layer disposed over the stent framework and supporting the drug-containing layer. The drug-containing layer may have an uneven coating thickness. In addition or in alternative, the drug-containing layer may be configured to significantly dissolve/dissipate/disappear between 45 days and 60 days after stent implantation. Stents may reduce, minimize, or eliminate patient risks associated with the implantation of a stent, including, for example, restenosis, thrombosis, and/or MACE.
