This invention relates to a preparation comprising a probiotic bacterial strainand a prebiotic mixture comprising 5-70 wt% of at least one N-acetylated oligosaccharideselected from the group comprising GalNAcαl,3Galβl,4Glc andGalβl,6GalNAcαl,3Galβl,4Glc, 20-95 wt% of at least oneneutral oligosaccharide selected from the group comprising Galβl,6Gal,Galβl,6Galβl,4Glc Galβl,6Galβl,6Glc, Galβl,3Galβl,3Glc,Galβl,3Galβl,4Glc, Galβ 1,6Galβ 1,6Galβ1,4GIc, Galβ 1,6Galβ 1,3Galβ 1,4GIc Galβ 1,3Galβ1,6Galβ 1,4GIc and Galβl,3Galβl,3Galβl,4Glc and2-50 wt% of at least one sialylated oligosaccharide selected from the group comprisingNeuAcα2,3Galβl,4Glc and NeuAcα2,6Galβl,4Glc.The invention extends to food products comprising said preparation and to theuse of the preparation in the prevention and treatment of infections.