This invention relates to a preparation comprising a probiotic bacterial strain and a prebiotic mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising Ga1NAcα1,3Ga1&bgr;1,4G1c and Ga1&bgr;1,6Ga1NAcα1,3Ga1&bgr;1,4G1c, 20-95 wt % of at least one neutral oligosaccharide selected from the group comprising Ga1&bgr;1,6Ga1, Ga1&bgr;1,6Ga1&bgr;1,4G1c Ga1&bgr;1,6Ga1&bgr;1,6G1c, Ga1&bgr;1,3Ga1&bgr;1,3G1c, Ga1&bgr;1,3Ga1&bgr;1,4G1c, Ga1&bgr; 1,6Ga1&bgr; 1,6Ga1&bgr; 1,4GIc, Ga1&bgr; 1,6Ga1&bgr; 1,3Ga1&bgr; 1,4GIc Ga1&bgr; 1,3Ga1&bgr; 1,6Ga1&bgr; 1,4GIc and Ga1&bgr;1,3Ga1&bgr;1,3Ga1&bgr;1,4G1c and 2-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga1&bgr;1,4G1c and NeuAcα2,6Ga1&bgr;1,4G1c. The invention extends to food products comprising said preparation and to the use of the preparation in the prevention and treatment of infections.