CHO JAE PYOUNG,LEE PUNG SOK,LEE SEUL A,JEONG MIN HO,LEE MASE
申请号:
IN10122/DELNP/2014
公开号:
IN2014DN10122A
申请日:
2014.11.27
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides a multilayer coating form (multilayer coated form) of pharmaceutical composition comprising an omega 3 fatty acid or an alkyl ester thereof and a statin based drug. More specifically the present invention provides an orally administered pharmaceutical composition comprising: (a) a gelatin capsule core containing an omega 3 fatty acid or an alkyl ester thereof (b) a first coating layer formed by coating onto the gelatin capsule core hydroxypropyl methylcellulose and a copolymer comprising a 1:2:1 weight ratio of butyl methacrylate and (2 dimethylaminoethyl) methacrylate and methyl methacrylate and (c) a second coating layer formed by coating onto the first coating layer a coating solution containing a statin based drug.