P. Jeffrey Conn,Craig W. Lindsley,Andrew S. Felts,Colleen M. Niswender,Rory A. Capstick,Paul K. Spearing,Sean R. Bollinger
申请号:
US16104011
公开号:
US10508105B2
申请日:
2018.08.16
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Indazole compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease states associated with glutamate dysfunction.