COMPOSES D'INDAZOLE UTILISES EN TANT QUE POTENTIALISATEURS ALLOSTERIQUES DE MGLUR4, COMPOSITIONS, ET METHODES DE TRAITEMENT DE DYSFONCTIONNEMENTS NEUROLOGIQUES
CONN, P. JEFFREY,LINDSLEY, CRAIG W.,FELTS, ANDREW,NISWENDER, COLLEEN M.,CAPSTICK, RORY A.,SPEARING, PAUL K.,BOLLINGER, SEAN
申请号:
CA3072493
公开号:
CA3072493A1
申请日:
2018.08.16
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Indazole compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease states associated with glutamate dysfunction.