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Heteroaryl compounds - 1,2,4 - triazole and tetrazole heteroaryl
专利权人:
ELANCO TIERGESUNDHEIT AG
发明人:
申请号:
ARP170100984
公开号:
AR108222A1
申请日:
2017.04.18
申请国别(地区):
AR
年份:
2018
代理人:
摘要:
a. Equation compound (1), where x is o or s, Q1 and Q2 are independent cr8309o or N, provided that at least one Q1 and Q2 is n, and is directly linked or ch832222;R¹ is H; C₁₋₆-alkyl optionally substituted with a substituent selected from: CN, CONH₂,COOH NO y -Si (CH)a. Halogenated tar c83218d31832626;C₂₋₆ alkenyl;C₂₋₆ haloalkenyl;1. C83228331 asphalt;Cal haloalkynyl;C₃₋₄ cycloalkyl-C₁₋₂ alkyl wherein C₃₋₄ cycloalkyl is optionally substituted with 1 to 2 halo atoms; oxetane-3-yl-CH₂;O replace with halogen or halogen tar c83321238o selectively;R 2 is phenyl, pyridine, pyridine, pyridine or pyridan. Among these substances, phenyl, pyridine, pyridine, pyridine or pyridan can be replaced by one or three substitutes, provided that these substitutes do not contain carbon (2) associated with the carbon of formula group,a. Each independently selected c8332123;Halogenated tar c83218323;thiohaloalkyl C₁₋₃,C₁₋₃ alkoxy,haloalkoxy C₁₋₃,halo, NO₂,SF8325,CN, CONH₂,COOH and C (s) nh832222;R3: c83216c833183237a or halide c83218333a;R⁴ is pyridine, pyrimidine, pyrazine or pyridazine, wherein pyridine, pyrimidine, pyrazine or pyridazine is optionally substituted with a substituent selected from: C₁₋₃ alkyl,Halogenated tar c83218323;C₁₋₃ alkoxy,cycloalkyl C₃₋₄,halo or hydroxy; R⁵ is H, C₁₋₃ alkyl,Halogenated tar c83218323;cycloalkyl C₃₋₄,C₁₋₃ alkoxy,alkoxy C₁₋₃C₍O₎₋ ₒ ₍ₐₗᶜₒˣⁱ C₁₋₃) ₂CH-;Or salt.Compuestos de fórmula (1) en donde: X es O ó S; Q¹ y Q² son independientemente CR⁵ o N, siempre que al menos uno de Q¹ y Q² sea N; Y es un enlace directo o CH₂; R¹ es H; alquilo C₁₋₆ opcionalmente sustituido con un sustituyente seleccionado de: CN, CONH₂, COOH, NO₂ y -Si(CH₃)₃; haloalquilo C₁₋₆; alquenilo C₂₋₆; haloalquenilo C₂₋₆; alquinilo C₂₋₆; haloalquinilo C₂₋₆; cicloalquil C₃₋₄-alquilo C₁₋₂ en donde cicloalquilo C₃₋₄ está opcionalmente sustituido con 1 a 2 átomos halo; oxetan-3-il-CH₂; o bencilo opcionalmente sustituido con halo o haloalquilo C₁₋₃; R² es fenilo, piridina, pirimidina, pirazi
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