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GEMINOID LIPOPEPTIDE COMPOUNDS AND THEIR USES
专利权人:
Erasmus University Medical Center Rotterdam;Stichting Katholieke Universiteit
发明人:
Bob Johan SCHOLTE,Martinus Christiaan FEITERS,Mark DAMEN
申请号:
US16310343
公开号:
US20190255141A1
申请日:
2017.06.16
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed are geminoid peptide-like compound according to Formula (I): R1—;C(=0)-Zn—;NR3—;R2 in which R1 and R2 are each independently saturated, partly saturated or unsaturated, straight, branched or cyclic alkyl chains, wherein R1 has a number of C atoms of 11 or more, preferably 11 to 19, and R2 has a number of C atoms of 12 or more, preferably 12 to 20; R3 is hydrogen or C1-C-6 alkyl; n is an integer from 1-15; each Z independently is an amino acid residue, wherein Zn comprises an N-terminus attached to C(=0) and a C-terminus that is attached to NR3, for use as a medicament.
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