The present invention provides a pharmaceutical preparation for use by injection into the skin, wherein the pharmaceutical preparation is preparable by a production method comprising the steps of providing a liquid collected from an organism, which liquid comprises cellular constituents of blood, providing a vessel or containment means, said vessel or containment means having an internal surface, and contacting said liquid with said vessel or containment means, wherein (a) said production method further comprises the step of incubating said liquid in said vessel or containment means for an incubation time, and optionally removing cellular constituents of said liquid after said incubation, (b) said liquid comprises exosomes, and said production method further comprises the steps of concentrating said exosomes and optionally removing cellular constituents of said liquid after said concentration, or the step of isolating said exosomes, or (c) said production method further comprises the step of avoiding incubation of said liquid, and the step of removing cellular constituents of said liquid contacted with said vessel or containment means.La presente invención proporciona una preparación farmacéutica para su uso por inyección en la piel, en donde la preparación farmacéutica se puede preparar mediante un método de producción que comprende las etapas de proporcionar un liquido recolectado de un organismo, cuyo liquido comprende componentes celulares de la sangre, proporcionando un recipiente o medios de contención, teniendo dicho recipiente o medios de contención una superficie interna, y poner en contacto dicho liquido con dicho recipiente o medios de contención, en donde (a) dicho método de producción comprende además la etapa de incubar dicho liquido en dicho recipiente o medios de contención durante un tiempo de incubación, y opcionalmente eliminar los componentes celulares de dicho liquido después de dicha incubación, (b) dicho liquido comprende exosomas, y dicho mét