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Synthetically functionalized living cells
专利权人:
Albert J. Swiston
发明人:
Albert J. Swiston,Michael F. Rubner,Robert E. Cohen,Darrell J. Irvine
申请号:
US12421162
公开号:
US08323637B2
申请日:
2009.04.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).
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