PARENTERALNA FARMACEUTSKA FORMULACIJA U SUSPENZIJI, KOJA IMA ODLOŽENO OSLOBAĐANJE, SA NISKOM I ULTRANISKOM DOZOM, U HORMONSKOJ TERAPIJI KLIMAKTERIČNOG SINDROMA
ÁNGELES, URIBE, JUAN,SAVOIR, VILBOEUF, JOHN, CLAUDE
申请号：
RSP20170622
公开号：
RS56142B1
申请日:
2010.12.14
申请国别(地区):
RS
年份:
2017
代理人:
摘要：
Parenteral pharmaceutical formulation or composition, in suspension, having sustained release, containing suspended particles of estradiol and progesterone for hormonal replacement in female mammals in low and ultralow dosage； the formulation consists of an injectable suspension comprising particles of estradiol, particles of progesterone, a surfactant agent, an isosmotic agent, a thickening agent, and one or more preservation agents, wherein the estradiol is in particles having a size between 1 and 100 microns and the progesterone is in particles having a size between 1 and 100 microns, for application thereof in parenteral, intramuscular, subcutaneous or intradermal pharmaceutical form.
