AB modulating peptides

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专利权人:

Alzhyme Pty Ltd

发明人:

Martins, Ralph,Verdile, Giuseppe,Taddei, Kevin,Barr, Renae

申请号：

AU2014339765

公开号：

AU2014339765A1

申请日:

2014.10.21

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

48 Abstract The present invention relates to an Aβ modulating peptide comprising a peptide selected from the list of peptides comprising: (i) Arg-Lys-Leu-Met-Gln-Pro-Thr-Arg-Asn (SEQ ID NO:1) (ii) Arg-Lys-Leu-Met-Gln-Pro-Thr-Arg-Asn-Arg-Arg-Asn-Pro-Asn-Thr (SEQ ID NO:2) (iii) a peptide according to (i) or (ii) wherein at least one of the amino acids is a D-amino acid (iv) a functional variant of a peptide according to any one of (i) to (iii) and (v) a peptide consisting of at least 3-5 contiguous amino acid residues of a peptide according to (i), (ii), (iii) or (iv). The present invention also relates to an Aβ modulating peptide comprising SEQ ID NO: 2 wherein all of the amino acids are D-amino acids.

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