BYSTROEM, STYRBJOERN,HARALDSSON, MARTIN,JOHANSSON, LARS,TEJBRANT, JAN
申请号:
HK11100172.7
公开号:
HK1146049B
申请日:
2011.01.10
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present invention relates to novel isoxazole compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides thereof, which are modulators of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the preparation of a medicament for the treatment of glaucoma.