Isoxazole derivatives as modulators of 11-beta-hydroxysteroid dehydrogenase type 1

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专利权人:

BIOVITRUM AB (PUBL)

发明人:

STYRBJÖRN BYSTRÖM,MARTIN HARALDSSON,LARS JOHANSSON,JAN TEJBRANT

申请号：

BRPI0907099

公开号：

BRPI0907099A2

申请日:

2009.01.16

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention relates to novel isoxazole compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides thereof, which are modulators of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the preparation of a medicament for the treatment of glaucoma.

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