PROBLEM TO BE SOLVED: To provide compositions and methods for inhibiting the growth of cancer stem cells or tumor initiating cells, for enhancing the biological effects of chemotherapeutic drugs or radiotherapy on cancer cells and/or for preventing cancer recurrence.SOLUTION: A method for inhibiting proliferation, survival or viability of a cancer stem cell (CSC) comprises contacting the CSC with a proliferation-, survival- or viability-inhibiting amount of a lysine specific demethylase (LSD) inhibitor.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】癌幹細胞又は腫瘍始原細胞の増殖を阻害し、癌細胞に対する化学療法剤又は放射線治療の生物学的効果を増強し、及び/又は癌の再発を予防するための組成物及び方法の提供。【解決手段】癌幹細胞（ＣＳＣ）の増殖、生残、又は生存を阻害する方法であって、ＣＳＣと増殖、生残、又は生存－阻害量のリジン特異的デメチラーゼ（ＬＳＤ）阻害剤を接触させることを含む方法。【選択図】なし
