A far-infrared emitters with physiological signal detection and method of operating the same is disclosed. A far-infrared beam module is switched on and generates far-infrared beam irradiating to a human body when a control unit starting up a microwave detecting module detecting physiological signal of the human body. The control unit is switched off when the time that the far-infrared beam irradiating on the human body reach a presetting period of time, thereby achieving the purpose of energy conservation.