Substantially pure vemurafenib and its salts

• 收藏
• 分享

专利权人:

SHILPA MEDICARE LIMITED

发明人:

Purohit Prashant,Nagnnath Kokare,Veera Reddy Yenireddy,Chaturvedi Akshay Kant

申请号：

US15527721

公开号：

US10414764B2

申请日:

2015.11.19

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).The present invention further relates to a process for the preparation substantially pure propane-1-sulfonic acid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide trifluoro methane sulfonic acid salt or Vemurafenib triflate of Formula (VII)

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/