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compound, pharmaceutical composition, use of a pharmaceutical composition, and methods for modulating androgen receptor activity and for increasing the bioavailability of an androgen receptor modulator
专利权人:
THE UNIVERSITY OF BRITISH COLUMBIA;BRITISH COLUMBIA CANCER AGENCY BRANCH
发明人:
Carmen Adriana Banuelos,JUN WANG,Javier Garcia Fernandez,Marianne Dorothy Sadar,Nasrin R. Mawji,Raymond John Andersen
申请号：
BR112015028174
公开号：
BR112015028174A2
申请日:
2014.05.09
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
1/1 summary â € œcompound, pharmaceutical composition, use of a pharmaceutical composition, and methods for modulating androgen receptor activity and for increasing the bioavailability of an androgen receptor modulator "Geno" compounds having a structure of structure i: i or a pharmaceutically acceptable salt, tautomer or 1 2 3 4 5 1 2 1 2 stereoisomer thereof, wherein r, r, r, r, r, j, j, x, z, n and n are 1 2 3 defined herein and where at least one of r, r or r is an alkyl, alkene, aryl or aralkyl ester, is provided . Uses of such compounds for treatment of various indications including prostate cancer as well as treatment methods involving such compounds are also provided.1 / 1 resumo “composto, composiã‡ãƒo farmacãšutica, uso de uma composiã‡ãƒo farmacãšutica, e, mã‰todos para modulaã‡ãƒo de atividade de receptores de andrã“geno e para aumentar a biodisponibilidade de um modulador de receptor de andrã“genoâ€� compostos tendo uma estrutura de estrutura i: i ou um sal farmaceuticamente aceitã¡vel, tautã´mero ou 1 2 3 4 5 1 2 1 2 estereoisã´mero do mesmo, em que r , r , r , r , r , j , j , x, z, n e n sã£o 1 2 3 definidas neste documento e em que pelo menos um dentre r , r ou r ã© um ã©ster alquil, alceno, aril ou aralquil, sã£o fornecidos. usos de tais compostos para tratamento de vã¡rias indicaã§ãµes, incluindo cã¢ncer de prã³stata, bem como mã©todos de tratamento envolvendo tais compostos tambã©m sã£o providos.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
