SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;ARAGON PHARMACEUTICALS, INC.
发明人:
SMITH, NICHOLAS, D,HERBERT, MARK, R,OUERFELLI, OUATHEK,DILHAS, ANNA
申请号：
PH12014502714
公开号：
PH12014502714B1
申请日:
2014.12.04
申请国别(地区):
PH
年份:
2015
代理人:
摘要：
Described herein are amorphous and crystalline forms of the androgen receptor modulator 4-[7-(6-cyano-5-trifluoromethylpyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide. Also described are pharmaceutical compositions suitable for administration to a mammal that include the androgen receptor modulator, and methods of using the androgen receptor modulator, alone and in combination with other compounds, for treating diseases or conditions that are associated with androgen receptor activity.
