A method for producing a customized, digitally-designed prosthesis in three patient interactions: a first patient interaction including acquiring a patient's intra-oral anatomy, natural anatomical measurements of the patient, and the tooth data of the patient for producing a first data set to design a first digital prosthesis, the first digital prosthesis being manufactured into a first denture base; a second patient interaction including seating the first denture base in the patient, adjusting the positioning of the teeth in the first denture base, and making an interocclusal record with the first denture base for creating a second data set to create a final digital denture, the final digital prosthesis being manufactured into a final prosthesis; and a third interaction where the dental practitioner seats the final prosthesis in the mouth of the patient.