A medical bandage (1; 20) comprising a substrate (2) comprising a first compound, the substrate having a first surface (4), wherein the medical bandage is the medical bandage A medical dressing, further comprising an adhesive layer (3) having a skin facing surface (6) for adhering to the skin surface, wherein at least a portion of said skin facing surface comprises a coating (9) comprising a second compound. Disclose. A method of manufacturing such a medical bandage is also disclosed.第1の化合物を含む基材(2)を備える医療用包帯(1;20)であって、前記基材は第1の表面(4)を有し、前記医療用包帯は、前記医療用包帯を皮膚表面に接着させるための皮膚対向面(6)有する接着層(3)を更に備え、前記皮膚対向面の少なくとも一部は第2の化合物を含むコーティング(9)を備える、医療用包帯を開示する。また、かかる医療用包帯を製造する方法も開示する。