A medical dressing (1；20) is disclosed, comprising a substrate(2)comprising a first chemical compound,said substrate having a first surface (4),wherein said medical dressing further comprises an adhesive layer(3)having a skin-facing surface(6)to adhere said medical dressing to a dermal surface, wherein at least a portion of said skin-facing surface comprises a coating (9) comprising a second chemical compound. Also disclosed is a method of manufacturing such a medical dressing.
