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2,5,6,7-tetrahydro- [1,4] oxazepin-3-ylamine or 2,3,6,7-tetrahydro- [1,4] oxazepin-5-ylamine compounds
专利权人:
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A.
发明人:
ALEXANDER V. MAYWEG,DIDIER ROMBACH,DAVID BANNER,EOIN POWER,HANS HILPERT,HARALD MAUSER,MARK ROGERS-EVANS,ROBERT NARQUIZIAN,ROLAND HUMM,THOMAS WOLTERING,WOLFGANG GUBA,WOLFGANG WOSTL
申请号:
BR112012028519
公开号:
BR112012028519A2
申请日:
2011.05.03
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
This invention relates to compounds of the formula wherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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