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2,5,6,7-tetrahydro-[1,4]oxazepin-3-ylamine or 2,3,6,7-tetrahydro-[1,4]oxazepin-5-ylamine compounds
专利权人:
Robert Narquizian;Hans Hilpert;Thomas Woltering;Wolfgang Guba;Mark Rogers-Evans;Alexander V. Mayweg;David Banner;Roland Humm;Didier Rombach;Eoin Power;Harald Mauser;Wolfgang Wostl
发明人:
David Banner,Wolfgang Guba,Hans Hilpert,Roland Humm,Harald Mauser,Alexander V. Mayweg,Robert Narquizian,Eoin Power,Mark Rogers-Evans,Didier Rombach,Thomas Woltering,Wolfgang Wostl
申请号:
US13096059
公开号:
US08673894B2
申请日:
2011.04.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention relates to compounds of the formulawherein A, B and R1 to R7 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or prophylactic treatment of diseases such as Alzheimer's disease, diabetes, particularly type 2 diabetes, and other metabolic disorders.
来源网站:
中国工程科技知识中心
来源网址:
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