Yue ZHANG;HANGZHOU DAC BIOTECH CO., LTD.;R. Yongxin ZHAO;Yourang MA
发明人:
R. Yongxin ZHAO,Yue ZHANG,Yourang MA
申请号:
US16782456
公开号:
US20200172480A1
申请日:
2020.02.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A conjugate of a potent cytotoxic agent with a cell-binding molecule having a structure represented by Formula (I), wherein T, L, m, n, , R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, and R13 are as defined herein, can be used for targeted treatment of cancer, autoimmune disease, and infectious disease.