CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS

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专利权人:

HANGZHOU DAC BIOTECH CO.; LTD

发明人:

ZHAO, ROBERT YONGXIN,ZHANG, YUE,MA, YOURANG

申请号：

CA2977032

公开号：

CA2977032A1

申请日:

2012.07.12

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

A conjugate of a potent cytotoxic agent with a cell-surface receptor bindingmoleculehaving a structure represented by Formula (I), wherein T, L, m, n, -----, R1,R2, R3, R4, R5, R6,R7, R8, R9, R10, R11, R12, and R13 are as defined herein, can be used fortargeted treatment ofcancer, autoimmune disease, and infectious disease.(see formula I)

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