Jennifer R. Allen,Matthew Paul Bourbeau,Ning Chen,Essa Hu,Roxanne Kunz,Shannon Rumfelt
申请号：
US13042410
公开号：
US08329700B2
申请日:
2011.03.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Pyrazine compounds of formula (I):or a pharmaceutically acceptable salt thereof, wherein m, n, p, R1, R2, R3, R4, X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, Y and Z are defined in the specification, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
