Jennifer R. Allen,Kristin L. Andrews,Michael J. Frohn,Paul E. Harrington,Alexander J. Pickrell,Robert M. Rzasa
申请号:
US13103858
公开号:
US08946230B2
申请日:
2011.05.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Aryl- and heteroaryl-nitrogen heterocyclic compounds of formula (I):or a pharmaceutically acceptable salt thereof, wherein m, p, q, R1, R2, R3, X1, X2, X3, Y1 and Y2 are defined herein and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntingtons Disease, bipolar disorder, obsessive-compulsive disorder, and the like.