PROBLEM TO BE SOLVED: To provide simple and safe techniques for the transdermal administration of polymer drugs, such as hydrophilic protein and the like, in which conventional percutaneous delivery techniques have not been able to be applied due to the difficulty of penetrating the stratum corneum.SOLUTION: A protein transdermal administration agent is a gel patch containing anionic or cationic gel containing protein, and gold nanorods whose surface are covered with a polymer having a polarity opposite to the polarity of the gel, the gold nanorods being bound to the surface on the gel.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【解決課題】角質層を透過しにくく従来の経皮デリバリー技術を適用できなかった親水性のタンパク質等の高分子薬物を簡便で安全に経皮投与する技術を提供する。【解決手段】タンパク質を含むアニオン性又はカチオン性のゲルと、当該ゲルの極性とは反対の極性を有するポリマーで表面が被覆され、当該ゲル表面に結合している金ナノロッドと、を含むゲルパッチであるタンパク質経皮投与剤。【選択図】なし
