A method and a device (100) for measuring mechanical property parameters of tissue. A data acquisition step (10) is continuously performed multiple of times, said step comprising: controlling an ultrasonic probe (101) to transmit an ultrasonic wave to target tissue (108), and receiving an echo of the ultrasonic wave to obtain first echo data； controlling the ultrasound probe (101) to transmit a focusing acoustic beam to a region of interest of the target tissue (108), so as to generate a propagation of a strain wave； within a resting time after the focusing acoustic beam is transmitted, the ultrasound probe (101) not transmitting an ultrasound signal to and/or receiving an ultrasound signal from the target tissue (108)； after the resting time ends, controlling the ultrasonic probe (101) to transmit an ultrasonic wave to the region of interest of the target tissue (108) again, and to receive the echo of the ultrasonic wave, so as to obtain second echo data. The mechanical property parameters of the target tissue (108) are calculated on the basis of multiple sets of first echo data and second echo data. By means of said method and device (100), the temporal resolution for measurement can be several times that of the single excitation detection method in the original technology, achieving accurate detection of wave velocity of a strain wave of biological soft tissue having high toughness.La présente invention concerne un procédé et un dispositif (100) pour mesurer des paramètres de propriété mécanique d'un tissu. Une étape d'acquisition de données (10) est réalisée en continu de multiples fois, ladite étape consistant à : commander une sonde ultrasonore (101) pour transmettre une onde ultrasonore à un tissu cible (108), et recevoir un écho de l'onde ultrasonore pour obtenir des premières données d'écho ； commander la sonde ultrasonore (101) pour transmettre un faisceau acoustique de focalisation à une région d'intérêt du tissu cible (108), de façon à générer une propag
