METHOD FOR THE SELECTION OF ANTIBODIES AGAINST BCMA

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专利权人:

ENGMAB AG

发明人:

VU, Minh Diem,STREIN, Klaus,MOESSNER, Ekkehard,HOSSE, Ralf,AST, Oliver,FREIMOSER-GRUNDSCHOBER, Anne,BACAC, Marina,FAUTI, Tanja,KLEIN, Christian,UMANA, Pablo,MOSER, Samuel

申请号：

HK16100577.3

公开号：

HK1212710A

申请日:

2016.01.20

申请国别(地区):

HK

年份:

2016

代理人:

摘要：

An antibody specifically binding to human BCMA, characterized in that the binding of said antibody is not reduced by APRIL and not reduced by BAFF, said antibody does not alter APRIL-dependent NF-κB activation, BAFF-dependent NF-κB activation, and does not alter NF-κB activation without BAFF and APRIL is useful as a therapeutic agent.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/