Ladyman, Heather Margaret,Tickle, Simon Peter,Popplewell, Andrew George
申请号:
AU2003223007
公开号:
AU2003223007C1
申请日:
2003.05.02
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human CD22. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a modified CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by cells expressing CD22.