POPPLEWELL, ANDREW GEORGE,TICKLE, SIMON PETER,LADYMAN, HEATHER MARGARET
申请号：
CA2484420
公开号：
CA2484420C
申请日:
2003.05.02
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
There is disclosed antibody molecules containing at least one CDR derived froma mouse monoclonal antibody having specificity for human CD22. There is alsodisclosed a CDR grafted antibody wherein at least one of the CDRs is amodified CDR. Further disclosed are DNA sequences encoding the chains of theantibody molecules, vectors, transformed host cells and uses of the antibodymolecules in the treatment of diseases mediated by cells expressing CD22.
