한국과학기술연구원;KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
发明人:
SIM, Tae Bo,심태보,YOON, Ho Jong,윤호종,KWAK, Yeon Ui,곽연의,HUR, Woo Young,허우영
申请号：
KRKR2016/008427
公开号：
WO2017/026718A1
申请日:
2016.08.01
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a novel 3-(isoxazol-3-yl)-pyrazolo[3,4-d]pyrimidin-4-amine compound, a preparation method for the compound, and a pharmaceutical use of the compound to be used in the prevention and treatment of various cancer diseases caused by the activity of RET kinases.La présente invention concerne un nouveau composé 3-(isoxazol-3-yl)-pyrazolo[3,4-d]pyrimidin-4-amine, un procédé de préparation pour le composé, et une utilisation pharmaceutique du composé pour la prévention et le traitement de diverses maladies cancéreuses provoquées par l'activité de kinases RET.본 발명은 신규 3-(이속사졸-3-일)-피라졸로[3,4-d]피리미딘-4-아민 화합물, 이 화합물 제조방법, 그리고 이 화합물의 RET 키나아제 활성으로 야기되는 각종 암질환의 예방 및 치료에 사용하는 의약용도에 관한 것이다.
