ALLGENESIS BIOTHERAPEUTICS INC.;AP BIOSCIENCES, INC.
发明人:
ZEN, KEVIN,WU, PEI-TZU,HER, JENG-HORNG,CHEN, HUANG-TSU,LEOU, JIUN-SHYANG,HSU, CHING-HSUAN
申请号:
CA2970384
公开号:
CA2970384A1
申请日:
2016.03.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Fusion proteins containing a PDGF binding portion, a VEGF binding portion, and an Fc antibody region are described. Also described are nucleic acids encoding the fusion proteins, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing clinical conditions characterized by abnormal angiogenesis, such as vascular permeability, edema or inflammation.