AN IMPROVED ONE-POT PROCESS FOR THE PREPARATION OF CHLORHEXIDINE

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专利权人:

发明人:

KHAMAR BAKULESH MAFATLAL,CHOWDHARY ANIL SHANKAR,SIDDIQUI ISHRAT HUSAIN,VYAS Chirag Jayantilal,CHRISTIAN Sandip Samualbhai,PATOLIYA PARESH UKABHAI,PANDIT UNNAT PRIYAVADAN,MODI INDRAVADAN AMBALAL

申请号：

IN2171/MUM/2011

公开号：

IN2011MU02171A

申请日:

2011.07.30

申请国别(地区):

IN

年份:

2013

代理人:

摘要：

AN IMPROVED ONE-POT PROCESS FOR THE PREPARATION OF CHLORHEXIDINE Abstract: The invention relates to an improved one pot process for the preparation of Chlorhexidine by reaction of hexamethylene diamine with sodium dicynamide in alcohol, using hydrochloric acid and a base, followed by reacting 1,1-hexane-1,6-diylbis(3-cyanoguanidine) [HMBDCA] with p-chloroaniline or its salt in presence of organic acid followed by basification and isolation of chlorhexidine by using lower alcohol.

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