PROCEDES ET COMPOSITIONS LIES A LA SURVIE AMELIOREE DE GLOBULES ROUGES HUMAINS DANS DES ANIMAUX NON HUMAINS IMMUNODEFICIENTS GENETIQUEMENT MODIFIES

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专利权人:

THE JACKSON LABORATORY

发明人:

SHULTZ, LEONARD D.,WILES, MICHAEL V.

申请号：

CA3033505

公开号：

CA3033505A1

申请日:

2017.08.11

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

A genetically modified immunodeficient non-human animal whose genome includes a genetic modification that renders the non-human animal deficient in macrophages and/or macrophage anti-human red blood cell activity so as to prolong the survival of human red blood cells when administered into said non-human animal is provided according to aspects of the present invention. Methods of assaying effects of putative therapeutic agents in such a genetically modified immunodeficient non-human animal are provided by the present invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/