THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF T;SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
发明人:
RONAI, Ze'ev,PINKERTON, Anthony B.,FENG, Yongmei,TOPISIROVIC, Ivan,BROWN, Kevin,HASSIG, Christian A.,RONAI, Zeev
申请号：
USUS2016/020273
公开号：
WO2016/140973A1
申请日:
2016.03.01
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided herein are compounds and pharmaceutical compositions comprising quinolinones. The quinolinones and compositions thereof are useful as eukaryotic translation initiation factor 4F (eIF4F) complex modulators.L'invention concerne des composés et des compositions pharmaceutiques comprenant des quinolinones. Les quinolinones et compositions associées sont utiles en tant que modulateurs du complexe du facteur d'initiation de traduction eucaryote 4F (eIF4F).
