BENTLEY, MICHAEL D.,CULBERTSON, SEAN,MCMANUS, SAMUEL P.
申请号：
CA2611823
公开号：
CA2611823C
申请日:
2006.06.16
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention provides conjugates having a degradable linkage andpolymeric reagents useful in preparing such conjugates. The conjugates as wellas the polymeric reagents used to form the conjugates include at least one ofeach the following: an aromatic moiety comprising an ionizable hydrogen atom,a spacer moiety, and a water-soluble polymer. Methods of making polymericreagents and conjugates, as well as methods for administering conjugates andcompositions, are also provided.
